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康宁杰瑞制药-B：JSKN022 IND申请获CDE正式受理_蜘蛛资讯网

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L1）/ 整合素αvβ6双特异性抗体偶联药物（ADC）JSKN022新药临床试验（IND）申请，已获中国国家药品监督管理局（NMPA）药品审评中心（CDE）正式受理。本公司计划开展用于治疗晚期恶性实体瘤的JSKN022首次人体临床研究。　　目前全球范围内尚无靶向整合素αvβ6或PD-L1的ADC上市，相关在研药物均处于临床研究阶段。临床前数据显示，JSKN022在体外和体内模型中，对整合素αvβ6

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